1 New Boss: Encounter an advanced and powerful alpha-mutant.
12 New Chapters : Four per act, plagued by horrific mutant adversaries.
3 New Crew Members: Loyal alien specialists eager to join the mission.
8 New Item Cards: Gruesome crew-mutations, and powerful new cybernetics.
4 New Dice: Three new crew dice, plus a 'Mutation die' used to determine the effects of certain chapters and items, as well as bringing a new challenge to the final battle.
New Mechanic: Mutations! Crew Members can now fall prey to mutations during the mission, warping their bodies and bringing about both negative and positive effects.